Clearing Tau Pathology with Aβ Immunotherapy—Reversible and Irreversible Stages Revealed
نویسندگان
چکیده
The report by Oddo and colleagues in this issue of Neuron demonstrates for the first time that clearance of amyloid also results in the removal of early-stage tau pathology in mice that develop both amyloid plaques and neurofibrillary tangles (NFT), the two hallmark lesions of Alzheimer's disease (AD). This result supports a primary role for Abeta in AD etiology.
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ورودعنوان ژورنال:
- Neuron
دوره 43 شماره
صفحات -
تاریخ انتشار 2004